Acute normovolemic hemodilution reduced allogeneic blood transfusion without increasing perioperative complications in patients undergoing free-flap reconstruction of the head and neck

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Blood transfusion prediction in patients undergoing major head and neck surgery with free-flap reconstruction.

OBJECTIVE to develop a clinically useful perioperative blood transfusion prediction model for patients undergoing a major head and neck surgical procedure requiring free-flap reconstruction. DESIGN retrospective observational study. SETTING tertiary care university-affiliated teaching hospital (University Health Network, Toronto, Ontario, Canada). PATIENTS all patients with a head and nec...

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Effectiveness of Moderate Acute Normovolemic Hemodilution Combined with Tranexamic Acid on the Reduction of Allogenic Blood Transfusion in Patients Undergoing Off-pump Coronary Artery Bypass

Introduction: There are different approaches to reduce the amount of blood loss and allogenic transfusion in cardiac surgery. Regarding this, the present study aimed to evaluate the blood sparing effect of acute normovolemic hemidilution (ANH) combined with intrao-perative tranexamic acid in patients undergoing off-pump coronary artery bypass (OPCAB).Material and Methods: This study was conduct...

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Acute normovolemic hemodilution effects on perioperative coagulation in elderly patients undergoing hepatic carcinectomy.

BACKGROUND Acute normovolemic hemodilution (ANH) has been widely used to prevent the massive blood loss during hepatic carcinoma. The influences of ANH on coagulation function are still controversy, especially in elderly patients. The study observed ANH effects on coagulation function and fibrinolysis in elderly patients undergoing the disease. MATERIALS AND METHODS Thirty elderly patients (a...

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Acute normovolemic hemodilution improves oxygenation in ischemic flap tissue.

BACKGROUND The flaps used in reconstructive surgery are prone to ischemia and hypoxia, which imply a considerable risk of wound-healing complications. During normovolemic hemodilution, the oxygenation may further deteriorate because of the lack of erythrocytes or improve because of increased microcirculatory blood flow. The aim of this study was to investigate the net effect of normovolemic hem...

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Absence of beneficial effect of acute normovolemic hemodilution combined with aprotinin on allogeneic blood transfusion requirements in cardiac surgery.

BACKGROUND The efficacy of acute normovolemic hemodilution (ANH) in decreasing allogeneic blood requirements remains controversial during cardiac surgery. METHODS In a prospective, randomized study, 80 adult cardiac surgical patients with normal cardiac function and no high risk of ischemic complications were subjected either to ANH, from a mean hematocrit of 43% to 28%, or to a control group...

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ژورنال

عنوان ژورنال: Journal of Anesthesia

سال: 2019

ISSN: 0913-8668,1438-8359

DOI: 10.1007/s00540-019-02714-5